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I had an other interesting story. A sim visited her sister. by chance at this exact moment the sister who I had no control over was giving birth. She glitched and got stuck in the Hospital. With her stats dropping I had to cheat and reset the family. I saved the game, loaded and after this story all the sims in town became unselectable I had to move sims out and start them on a new map to fix it. Just a crazy story to share.
I haven't seen this happen with any of my Sims, but it happens when I (rarely) start a new game in Sunset Valley. Claire Ursine glitches sometimes when she goes into labor and I've had to end her pregnancy a couple of times (or more).
People who play in one world for a long time will usually get these glitches, there may be some mods to fix it but it's easier to just move into another world.