I have the following The Sims 2 Holiday Pack,University,Nightlife installed, not installed now but will be shortly Open for Business,Family Fun Sturff.
I have install 3 of the 5 game is this Sim Family not appearing on the Lot can The Sims 2 Holiday Pack make the game do strange thing,like the Custom Conent not working right

Neither the "The Sims 2: Holiday Edition" nor "The Sims 2: Holiday Party Pack (HPP)" will "make the game do strange things". The first is just the base game with the items from HPP. HPP is just a booster pack. Did you install them to the default install location?